Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1248 | Thyroid (non-cancer) | ECE2017

Intrathyroidal and peripheral venous blood lymphocyte subset patterns in patients with Graves disease

Dudina Margarita , Sergey Dogadin , Andrey Savchenko , Vladimir Mankovsky , Alexander Borisov

GravesÂ’ disease (GD) is an autoimmune disease with genetic predisposition. The link with the major histocompatibility complex determines the complexity of the excess thyroid hormones molecular action on immune system that may cause the divergence of autoimmune process in GD, functioning not only in peripheral immune cells, but also in the thyroid. Objective: to study the phenotypic composition of T- and B-lymphocyte subset patterns in peripheral blood and thyroid tissue i...